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MIT/Mayo Physical Sciences Center for Drug Distribution and Drug Efficacy in Brain Tumors
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Uridine
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2022
Pal S, Kaplan JP, Nguyen H, Stopka SA, Savani MR, Regan MS, De Nguyen Q-, Jones KL, Moreau LA, Peng J et al.
. 2022.
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
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Cancer Cell. 40(9):957-972.e10.
News & Events
MIT PS-OC Mini-Symposium
May 30, 2017
Ludwig Center Oncology Seminar
May 8, 2017
Recent Publications
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers.
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma.
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