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MIT/Mayo Physical Sciences Center for Drug Distribution and Drug Efficacy in Brain Tumors
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Antigens, Neoplasm
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2022
Stopfer LE, Rettko NJ, Leddy O, Mesfin JM, Brown E, Winski S, Bryson B, Wells JA, White FM
. 2022.
MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.
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Proc Natl Acad Sci U S A. 119(49):e2208900119.
News & Events
MIT PS-OC Mini-Symposium
May 30, 2017
Ludwig Center Oncology Seminar
May 8, 2017
Recent Publications
MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.
Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial.
Oncometabolite d-2HG alters T cell metabolism to impair CD8 T cell function.
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
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