Publications
Found 53 results
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma.. Cell Rep. 39(12):110991.
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2022. Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial.. Lancet Oncol. 23(11):1409-1418.
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2022. De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.. Cancer Cell. 40(9):939-956.e16.
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2022. A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.. Cancer Cell. 40(9):957-972.e10.
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2022. Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer.. Cancers (Basel). 14(17)
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2022. MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.. Proc Natl Acad Sci U S A. 119(49):e2208900119.
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2022. Multimodal platform for assessing drug distribution and response in clinical trials.. Neuro Oncol. 24(1):64-77.
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2022. Oncometabolite d-2HG alters T cell metabolism to impair CD8 T cell function.. Science. 377(6614):1519-1529.
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2022. Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers.. PLoS One. 17(9):e0261803.
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2022. 1,2,3, MHC: a review of mass-spectrometry-based immunopeptidomics methods for relative and absolute quantification of pMHCs.. Immunooncol Technol. 11:100042.
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2021. Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants.. Proc Natl Acad Sci U S A. 118(37)
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2021. Bringing Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging to the Clinics.. Clin Lab Med. 41(2):309-324.
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2021. Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma.. Neuro Oncol. 23(12):2042-2053.
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2021. High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors.. Cancer Res. 81(9):2495-2509.
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2021. Leveraging Immunopeptidomics To Study and Combat Infectious Disease.. mSystems. 6(4):e0031021.
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2021. Peak learning of mass spectrometry imaging data using artificial neural networks.. Nat Commun. 12(1):5544.
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2021. Phosphoproteomics: a valuable tool for uncovering molecular signaling in cancer cells.. Expert Rev Proteomics. 18(8):661-674.
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2021. Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient-specific signaling networks.. Cancer Res.
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2021. Quantitative consequences of protein carriers in immunopeptidomics and tyrosine phosphorylation MS analyses.. Mol Cell Proteomics. :100104.
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2021. Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity.. Elife. 9
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2020. Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma.. Cancer Res. 80(6):1258-1267.
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2020. Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.. Mol Syst Biol. 16(12):e9819.
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2020. Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022.. Clin Breast Cancer. 20(2):145-151.e2.
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2020. Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.. Cell Syst. 11(5):478-494.e9.
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2020. The 2019 mathematical oncology roadmap.. Phys Biol. 16(4):041005.
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2019.