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MIT/Mayo Physical Sciences Center for Drug Distribution and Drug Efficacy in Brain Tumors
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Mice, Knockout
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2018
Gampa G, Kim M, Cook-Rostie N, Laramy JK, Sarkaria JN, Paradiso L, DePalatis L, Elmquist WF
. 2018.
Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases.
.
Drug Metab Dispos. 46(5):658-666.
News & Events
MIT PS-OC Mini-Symposium
May 30, 2017
Ludwig Center Oncology Seminar
May 8, 2017
Recent Publications
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma.
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers.
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma.
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